Basic Pancreatic Trypsin Inhibitor



Basic Pancreatic Trypsin Inhibitor (BPTI) is a small protein which inhibits trypsin and related proteases. The images at the left and at the right correspond to one representative BPTI, i.e. the crystal structure of bovine BPTI (1bpi).

BPTI
2zvx, 2zjx, 1g6x, 1qlq, 1bti, 1fan, 1nag, 1bpt, 7pti, 8pti – bBPTI (mutant) - bovine

3ci7 - BPTI (mutant) – synthesized

2by5, 2by6, 2by7, 2by8, 2by9, 2bya, 1k6u, 1bhc, 1bpi - bBPTI

1uua – bBPTI truncated – NMR

1uub - bBPTI truncated (mutant) – NMR

1oa5, 1oa6 – bBPTI – NMR

1ld5, 1ld6, 1jv8, 1jv9 - bBPTI (mutant) – NMR

BPTI+protease
3fp6 – rBPTI+anionic trypsin – rat

3tgi - bBPTI+anionic trypsin

1co7, 1f5r, 1f7z, 3tgk - rBPTI+anionic trypsin (mutant)

3tgj - bBPTI+anionic trypsin (mutant)

3fp7, 3fp8, 1fy8 – rBPTI (mutant) +anionic trypsin

2r9p – bBPTI+hMesotrypsin (mutant)

2ra3 - bBPTI+hTrypsin cationic (mutant)

2ijo – bBPTI+West Nile virus protease

1ykt – bBPTI+rTrypsin II (mutant)

1ylc, 1yld - bBPTI (mutant)+ rTrypsin II (mutant)

2ftl, 3btk - bBPTI+bTrypsin cationic

1brb - bBPTI+rTrypsin cationic

2ftm, 2fi3, 2fi5, 1ejm – bBPTI (mutant)+bTrypsin cationic

3bte, 3btq, 3btd, 3btf, 3btg, 3bth, 3btm, 3btt, 3btw, 1aal, 6pti - bBPTI (mutant)+bTrypsin

2fi4 - bBPTI (mutant)+bTrypsin cationic (mutant)

1t7c, 1t8l - bBPTI (mutant)+bChymotrypsin

1cbw, 1mtn - bBPTI+bChymotrypsin A

1t8m, 1t8n, 1t8o - bBPTI +bChymotrypsin A (mutant)

1p2i, 1p2j, 1p2k - bBPTI (mutant)+bTrypsinogen

1p2m, 1p2n, 1p2o, 1p2q - bBPTI (mutant)+bChymotrypsinogen A

1eaw – bBPTI+hMatriptase

1d0d – bBPTI+anticoagulant protein – tick